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Neurological and Cognitive Effects of Hypothyroidism in Patients With Epilepsy: A Study on Anti‐Seizure Medicines Therapy

Authors: Natalia Molodozhnikova,Svetlana Prokhorova,Dimitar Monov,Nikolay Lilyanov
Publisher: Wiley
Publish date: 2025-1
ISSN: 0360-4012,1097-4547 DOI: 10.1002/jnr.70012
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The study acknowledges that the duration of ASM use and adherence were not systematically recorded, which is a major limitation. These factors are crucial because prolonged use of ASMs, especially at higher doses, has been linked to cognitive impairments and thyroid dysfunction. Without controlling for these variables, it is difficult to isolate the specific effects of hypothyroidism on cognitive function. 

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