The paper discusses various nanocarrier types, However a direct quantitative comparison of their performance metrics, such as encapsulation efficiency, controlled release profiles, and stability under physiological conditions, is missing. Were there any studies systematically evaluating these parameters across different formulations?
The paper extensively covers lipid-based nanocarriers’ advantages, but their limitations in real-world applications remain underexplored. For example, issues related to large-scale production, cost-effectiveness, and regulatory hurdles are only briefly mentioned. Given the increasing demand for scalable drug delivery systems, how do the authors foresee overcoming these challenges? Have there been any successful case studies demonstrating industrial feasibility?