The review highlights natural compounds as promising alternatives, but how do they compare to standard UTI treatments in terms of efficacy? Were any direct comparisons with antibiotics included in the reviewed studies?
While the antibacterial potential of various phytochemicals is discussed, their pharmacokinetics and bioavailability in humans are not well addressed. Have any formulation strategies, like nanoencapsulation, been explored to improve their therapeutic effectiveness?
There is limited discussion on human trials. Are there standardized extracts or clinical studies confirming the effectiveness of these natural compounds in UTI treatment?