In your strategy for constructing CMOFs via preassembled metal complexes/clusters with reactive sites (e.g., –CHO, –NH₂) linked through dynamic covalent chemistry (DCC), you emphasize enhanced structural predictability and chemical stability. However, considering that imine-based linkages are known to exhibit limited hydrolytic stability, particularly under humid or acidic conditions, how do you reconcile this with your claim of “high chemical stability even under harsh conditions”?
Moreover, has any quantitative assessment (e.g., long-term water stability tests, pH-cycling durability, or catalytic performance retention in aqueous media) been conducted to support this stability claim, especially in comparison to conventional MOFs or COFs? If not, do you consider the imine-based DCC approach fundamentally limiting the application of CMOFs in environments requiring moisture or pH robustness?