The study convincingly demonstrates the role of RsmA in enhancing peanut immunity, but its mechanism remains unclear. The authors conclude that RsmA acts as an elicitor based on its ability to induce immune responses in plants. However, the study also states that RsmA is not secreted via the Type III Secretion System (T3SS) or translocated into host cells, as shown by the cAMP assay results. This raises questions about how RsmA interacts with host immune signaling pathways if it does not rely on common bacterial effector secretion systems.
Could the authors clarify whether alternative secretion mechanisms or indirect pathways, such as extracellular release or interactions through bacterial surface structures, were considered? Further exploration of how RsmA reaches its target in the host could provide a more comprehensive understanding of its function and potential applications in resistance breeding.