Dear Authors,
We appreciate your valuable contribution to this field. However, we noted a few critical concerns in your study. Specifically, the lack of robust causality assessments undermines the reliability of attributing adverse drug events (ADEs) to specific active pharmaceutical ingredients. Additionally, discrepancies in case counts and insufficient methodological details (e.g., FAERS data extraction criteria) limit the reproducibility of your findings. We kindly request that these issues be addressed to enhance the clarity and validity of your work.